TABLE 1.
Chow | Chow + 0.3% Cholesterol | |
---|---|---|
Body weight (g) | 113.2 ± 1.7 | 116.9 ± 1.5 |
Fasted blood glucose (mg/dl) | 82.5 ± 3.0 | 96.0 ± 2.4*** |
Total cholesterol (g/l) | 1.31 ± 0.06 | 2.87 ± 0.10*** |
HDL-cholesterol (g/l) | 0.95 ± 0.05 | 1.67 ± 0.11*** |
Non-HDL-cholesterol (g/l) | 0.36 ± 0.03 | 1.20 ± 0.09*** |
HDL-cholesterol/total cholesterol | 0.72 ± 0.02 | 0.58 ± 0.03*** |
Triglycerides (g/l) | 1.06 ± 0.05 | 1.39 ± 0.12* |
Free fatty acids (mmol/l) | 0.66 ± 0.07 | 0.68 ± 0.04 |
CETP activity (pmol/h/µl) | 5.37 ± 0.36 | 7.14 ± 0.61** |
PLTP activity (pmol/min/µl) | 0.75 ± 0.02 | 1.36 ± 0.02*** |
LCAT activity (AU) | 7.74 ± 0.13 | 8.39 ± 0.13** |
HL activity (pmol/min/ml) | 3.66 ± 0.14 | 3.96 ± 0.31 |
Mean ± SEM, n = 8 per group, *P < 0.05, **P < 0.01, ***P < 0.001 vs. chow.