FIG. 6.

Crystal structure of EcDOS heme showing rearrangments in heme pocket on oxygen binding. (A) EcDOS-O₂ (yellow) with His77 (below the heme plane) in the proximal position and O₂ as two red spheres above the heme. (B) Deoxygenated EcDOS (red). Amino acids are numbered according to EcDOS sequence. (Reproduced with permission from ref. 111). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article at www.liebertonline.com/ars).