Table 3.
Ten FDA-approved hypnotics for insomnia
| Name | Trade name | Indication | Dose mg | Half-life hours |
|---|---|---|---|---|
| Flurazepam | Dalmane | Short-term treatment | 15 | 47–100 |
| HCL | 30 | |||
| Quazepam | Doral | Short-term treatment | 7.5 | 39–73 |
| 15 | ||||
| Estazolam | ProSom | Short-term treatment | 0.5 | 10–24 |
| 1 | ||||
| 2 | ||||
| Temazepam | Restoril | Short-term treatment | 7.5 | 3.5–18.4 |
| 15 | ||||
| 30 | ||||
| Triazolam | Halcion | Short-term treatment | 0.125 | 1.5–5.5 |
| 0.25 | ||||
| Zaleplon | Sonata | Short-term treatment of sleep onset insomnia | 5 | 1 |
| 10 | ||||
| 20 | ||||
| Zolpidem | Ambien | Short-term treatment of sleep onset insomnia | 5 | 2.5 |
| 10 | ||||
| Zolpidem | Ambien | Long-term treatment of sleep onset or mainte- nance insomnia | 6.25 | 2.8 |
| MR | CR | 12.5 | ||
| Eszopiclone | Lunesta | Long-term treatment of sleep onset or mainte- nance insomnia | 1 | 6 |
| 2 | ||||
| 3 | ||||
| Ramelteon | Rozerem | Long-term treatment of sleep onset insomnia | 8 | 1–2.6 |