Table 2.
Equivalent concentrations of BPDE-HSA adduct from the current study and from previous studies of PAH-exposed-exposed workers and control subjects which employed the competitive ELISA format.
| Study | ELISA | Exposure Group | Location | No. Subj. | BPDE Equivalents (fmol/mg HSA) | Fold Ratio (Exposed: Controls) |
|---|---|---|---|---|---|---|
| Current | Sandwich | Coke-oven workers (smoking & nonsmoking) | China | 10 | 1010 (GM) | 35 |
| Sandwich | Steel-factory control workers (smoking & nonsmoking) | China | 10 | 220 (GM) | 7.6 | |
| Sandwich | Unexposed controls (nonsmoking) | U.S.A. | 10 | 28.9 (GM) | ||
| Kure et al. (19) | Competitive | Coke-oven workers (smoking & nonsmoking) | Norway | 38 | 3920 (GM) | 1.5 |
| Competitive | Controls (smoking & nonsmoking) | Norway | 45 | 2620 (GM) | ||
| Lee et al. (3) | Competitive | Foundry workers (nonsmoking) | Finland | 13 | 5020 (GM) | 1.4 |
| Competitive | Controls (nonsmoking) | Finland | 10 | 3600 (GM) | ||
| Competitive | Roofers (nonsmoking) | U.S.A. | 12 | 4020 (GM) | 1.5 | |
| Competitive | Controls (nonsmoking) | U.S.A. | 12 | 3280 (GM) | ||
| Omland et al. (21) | Competitive | Foundry workers (nonsmoking) | Denmark | 25 | 580 (median) | 0.83 |
| Competitive | Controls (nonsmoking) | Denmark | 26 | 700 (median) | ||
| Sherson et al. (20) | Competitive | Foundry workers (nonsmoking) | Denmark | 19 | 200 (median) | 5.6 |
| Competitive | Controls (nonsmoking) | Denmark | 19 | 35.9 (median) | ||
Legend: GM, geometric mean.