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. Author manuscript; available in PMC: 2010 Mar 24.
Published in final edited form as: Nature. 2009 Sep 24;461(7263):489–494. doi: 10.1038/nature08365

Figure 2.

Figure 2

Linkage disequilibrium based evidence for founder events in India. For each pair of samples, we calculate the autocorrelation of the number of shared alleles as a function of distance, recognizing that SNP genotypes should differ by at most one allele in regions of identity by descent. To correct for background allele sharing, we subtract the same quantity comparing across groups. Allele sharing in the Vysya decreases with an exponential decay of 0.461 cM as shown here, suggesting a founder event roughly 100/(2*0.461) = 108 generations ago. We present similar analyses for all Indian groups in Figure S2.