Table 1.
Patient Demographics
| Criteria | Control Subjects | Mild to Moderate Asthmatic Subjects |
|---|---|---|
| Number | 16 | 18 |
| Sex (M/F) | 6/10 | 7/11 |
| Age, yr | 25.2 ± 6.0 | 25.9 ± 9.4 |
| Antileukotrienes | 0 | 2 |
| Inhaled Steriods | 0 | 9 |
| FEV1 % predicted | 105.6 ± 11.4 | 90.2 ± 14.3‡ |
| FEV1/FVC % predicted | 101.5 ± 4.1 | 87.6 ± 9.8§ |
| PC20 (mg/ml) | >16 | 1.0 (0.48-2.1)† |
| Squamous cells (%) | 1.5 (3.8)* | 2.0 (6.0)* |
| Lung Epithelial cells (%) | 2.0 (5.3)* | 2.5 (3.0)* |
| Eosinophils (%) | 1.1 (3.0)* | 2.0 (6.0)* |
| Neutrophils (%) | 19.85 (21.1)* | 6.95 (17.8)* |
Values are reported as means ± SD unless otherwise indicated. Definition of abbreviations: F = females, FEV1 = forced expiratory volume in 1 second, FEV1/FVC = FEV1/forced vital capacity, M = males, PC20 = provocation concentration of methacholine causing a 20% fall in FEV1. The percentage of eosinophils and neutrophils are reported for induced sputum.
†Geometric mean (range)
*Median (interquartile range)
‡p = 0.004, asthmatic vs. control group
§p < 0.0001, asthmatic vs. control group