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. 2010 Mar 22;5(3):e9804. doi: 10.1371/journal.pone.0009804

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Jones et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Weekly passive transfer of 2 mg PrioV3 antibody for 60 days induced substantial reduction in splenic PrP^Sc levels when treatment was started at day 10 p.i. CD71-treated as well as untreated mice did not inhibit splenic prion replication and this reduction was not observed.