Table 3.

Logistic Regression Models Evaluating The Relationship Between Circulating Levels of Estradiol (Total and Free) (Predictors) and Metabolic Syndrome (Outcome) in Older Men.

Variable	O.R. [95%CI]	P value*
Age-adjusted Log (Total Estradiol) (pmol/L)	2.69 [1.38–5.24]	0.004
Age-adjusted Log (Free Estradiol) (pmol/L)	3.35 [1.84–6.07]	<.0001
Model 1*
Log (Total Estradiol) (pmol/L)	2.31 [1.39–4.70]	0.02
Log (Free Estradiol) (pmol/L)	2.69 [1.38–5.24]	<0.001
Model 2 (Model 1+BMI + log (SHBG)+ total testosterone +log (DHEAS))
Log (Total Estradiol) (pmol/L)	2.61 [0.96–6.85]	0.053
Log (Free Estradiol) (pmol/L)	2.59 [1.01–6.66]	0.048
Model 3 (Model 1+ BMI)
Log (total Estradiol) (pmol/L)	1.79 [0.77–4.09]	0.18
Log (Free Estradiol) (pmol/L)	2.11 [1.03–4.33]	0.041

^*Model 1: each line refers the results of a separate model adjusted for age, smoking, alcohol, physical activity, log (IL-6) and log (Insulin).