Table 3.

FZD1 Haplotype Associations with Femoral Neck BMD and Geometry in Afro-Caribbean Men

Trait	Haplotype Mean (SE)			p-value*
	0	1	2
GG	N=119	N=506	N=692
BMD (g/cm2)	1.034 (0.014)	1.050 (0.007)	1.053 (0.006)	0.221d
Cross-sectional Area (cm2)	3.133 (0.039)	3.192 (0.019)	3.169 (0.016)	0.272d
Subperiosteal Width (cm)	3.191 (0.019)	3.197 (0.009)	3.171 (0.008)	0.026 r
Cross-sectional Moment of Inertia (cm4)	2.709 (0.047)	2.758 (0.023)	2.688 (0.019)	0.031 r
GC	N=1140	N=172	N=5
BMD (g/cm2)	1.052 (0.005)	1.040 (0.012)	1.036 (0.069)	0.329d
Cross-sectional Area (cm2)	3.179 (0.013)	3.142 (0.033)	3.172 (0.191)	0.292d
Subperiosteal Width (cm)	3.183 (0.006)	3.181 (0.015)	3.220 (0.090)	0.949d
Cross-sectional Moment of Inertia (cm4)	2.720 (0.015)	2.694 (0.039)	2.808 (0.228)	0.591d
TC	N=825	N=422	N=70
BMD (g/cm2)	1.052 (0.005)	1.045 (0.007)	1.050 (0.018)	0.456d
Cross-sectional Area (cm2)	3.170 (0.015)	3.182 (0.021)	3.185 (0.051)	0.618d
Subperiosteal Width (cm)	3.172 (0.007)	3.200 (0.010)	3.194 (0.024)	0.018 d
Cross-sectional Moment of Inertia (cm4)	2.693 (0.018)	2.758 (0.025)	2.749 (0.061)	0.029 d

^*p-values of the best fit model adjusted for age, height and weight are shown:

^ddominant model;

^rrecessive model

0, zero copies of the haplotype; 1, one copy of the haplotype; 2, two copies of the haplotype. SE, standard error of the mean.