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Calcium homeostasis. Simultaneous measurements of [Ca2+]c and ΔΨm were made from neurons (A–B) and astrocytes (C–D) in mixed culture co-loaded with fura-2 and rhodamine 123. Traces are shown from single cells in each case. Mitochondrial mutations did not induce pathological changes in their mitochondrial responses to [Ca2+]c signals under these conditions.
