Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Tumor necrosis factor (TNF) α and interferon (IFN) γ induce formation of immunoproteasome subunits. LMP7, LMP2 and MECL-1 subunits replace the constitutive catalytic subunits β5, β1 and β2, respectively, which shift the catalytic properties of the proteasome to generate MHC-I-binding peptides.
