Figure 5. Survival of dprx5^−/− mutant under normal (A) and oxidative stress (B) conditions.

(A) Pooled data of three independent experiments are shown for each line. In all experiments, 200–250 flies for each fly strain were used. The median age was 43 ± 16 and 40 ± 12 days and mean life span was 65.3 and 57.4 days for y w and dprx5 strains correspondingly. There were no significant differences in maximum age (10% survival) between y w strain and dprx5^−/− mutant, which in both cases was 53–54 days. (B) Approx. 100–150 flies of each group (dprx5 mutant and y w control) were fed 1% sucrose solution containing 10 mM paraquat or 0.5 M H₂O₂. Results are means ± S.D. of two independent experiments.