Table 1 .
Expression of axotrophin/MARCH-7 in human tissues
| Tissue | Cell or tissue type | % of positive cells | Intensity |
|---|---|---|---|
| Adrenal | Medulla | 100 | ++++ |
| Appendix | Glandular epithelium | 100 | ++++ |
| Lymphocytes | 50 | ++ | |
| Bone marrow | Megakaryocyte | 100 | ++++ |
| Other | 40 | ++++ | |
| Breast | Ductal epithelial | 100 | +++++ |
| Bronchus | Glandular epithelium | 100 | +++++ |
| Plasma cells | 100 | ++++ | |
| Cerebellum | Neurons | 100 | ++++ |
| Glia | Negative | Negative | |
| Cervix | Squamous epithelium | 100 | + |
| Colon | Glandular epithelium | 100 | +++++ |
| Plasma cells | 100 | ++++ | |
| Duodenum | Glandular epithelium | 100 | +++++ |
| Plasma cells | 70 | ++ | |
| Epididymis | Ciliated glandular epithelium | 100 | +++ |
| Esophagus | Squamous epithelium | 100 | +++++ |
| Fallopian tube | Ciliated glandular epithelium | 100 | +++++ |
| Gall bladder | Glandular epithelium | 100 | ++++ |
| Heart muscle | Myocytes | 100 | ++++ |
| Hippocampus | Neurons | 100 | +++++ |
| Glia | Negative | Negative | |
| Neuropil | 20 | + | |
| Kidney | Tubular epithelium | 100 | ++++ |
| Glomeruli | Negative | Negative | |
| Lateral ventricle | Neuropil | 20 | ++ |
| Glia | Negative | Negative | |
| Lung | Pneumocytes | Negative | Negative |
| Alveolar macrophages | 20 | + | |
| Lymph node | Lymphocytes (some T-cell patches) | 20 | +++ |
| B cell areas | Negative | Negative | |
| Nasopharynx | Glandular epithelium | 100 | ++++ |
| Oral mucosa | Squamous epithelium | 20 | + |
| Ovary | Endothelium | 50 | +++ |
| Scattered stromal cells | 30 | ++ | |
| Pancreas | Acinar | 100 | +++++ |
| Islets | 100 | +++ | |
| Prostate | Glandular epithelium | 100 | ++++ |
| Rectum | Glandular epithelium | 100 | ++++ |
| Salivary gland | Acinar and ductal epithelium | 100 | ++++ |
| Seminal vesicle | Ductal epithelium | 100 | ++++ |
| Skeletal muscle | Myocytes | 100 | ++++ |
| Skin | Keratinocytes | 50 | ++ |
| Spleen | Endothelial sinusoids | 100 | ++++ |
| Lymphocytes | 5 | ++ | |
| Lymphocytes | 90 | Negative | |
| Small intestine | Glandular epithelium | 100 | +++++ |
| Crypt basal cells | ++++ | ||
| Smooth muscle | Myocytes | Negative | Negative |
| Vascular endothelium | Endothelial | 30 | ++ |
| Stromal spindle cells | Negative | Negative | |
| Fat | Adipocytes | Negative | Negative |
| Peripheral nerve | Nerve | Negative | Negative |
| Lymphocytes | Negative | Negative | |
| Plasma cells | 5 | +++++ | |
| Stomach | Glandular epithelium | 100 | +++++ |
| Testis (from 26-year-old) | Sertoli cells | Negative | Negative |
| Early germ cells | 20 | ++ | |
| Maturing sperm cells | Negative | Negative | |
| Testis (from 26-year-old) | Spermatozoa | Negative | Negative |
| Leydig cells | 100 | ++++ | |
| Testis (from 46-year-old) | Sertoli cells | 100 | ++ |
| Germ cells | 100 | ++ | |
| Leydig cells | 100 | ++++ | |
| Thyroid gland | Follicular epithelium | 100 | ++++ |
| Trophoblast | Epithelium | 100 | ++++ |
| Trophoblast | 100 | +++++ | |
| Urinary bladder | Transitional epithelium | 100 | ++++ |
| Vagina | Squamous epithelium | Negative | Negative |
| Vulva | Epidermis | Negative | Negative |