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Course of infection of M. tuberculosis H37Rv in Rat lungs following low-grade aerosol infection. (▴): Course of infection and CFU obtained during weeks 1–7 in study 1. (■): Course of infection and CFU obtained over weeks 2–18 in study 2. Drug treatment started at week 4 postinfection. Inset shows a rat lung at thirteen-week post infection with multiple macroscopic nodular granulomas all the lung lobes following aerosol infection with M. tuberculosis.
