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. Author manuscript; available in PMC: 2010 Mar 22.
Published in final edited form as: Genomics. 2006 Aug 17;88(5):580–590. doi: 10.1016/j.ygeno.2006.06.015

Fig. 6.

Fig. 6

(A–E) Electron micrographs of lumbar DRG from 20-month-old YG8 rescue mice showing examples of: (A) giant vacuoles, (B) chromatolysis, and (C) lipofuscin deposits within the large neuronal cell bodies. Also detected within the lumbar DRG are instances of: (D) complete demyelination of a large axon with its associated Schwann cell and (E) large axonal swelling with reduced myelination. (F) Electron micrograph of cardiac muscle from a 20-month-old YG8 rescue mouse showing lipofuscin deposition and lysosomes disrupting an ordered array of mitochondria. Scale bars represent 10 μm.