Fig. (1). NGF gene transfer restores impaired sensory innervation in diabetic hearts.

Recording of impulse activity from cardiac sympathetic afferent nerves. Myocardial ischemia was induced at the time point indicated by arrows. Note that the response of cardiac afferent nerves was reduced in DM injected with p-con (control). The gene transfer of 50 μg p-NGF preserved cardiac sensory nerve function in DM.