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. 2010 Mar 21;2010:940741. doi: 10.1155/2010/940741

Table 1.

A schematic view of transepithelial ion transport functions through the chorionic epithelium.

Functions Sites and mechanisms Molecular and structural components References
Calcium reabsorption from the eggshell Capillary covering cells: pinocytosis model [6, 12, 13, 15, 19, 3538, 40, 56]
Tight adhesion of cell membranes to shell membrane, apical vesiscles, and endocytotic-like pits [4, 6, 15, 17, 31, 35, 36, 48, 56]
Ca2+-binding protein [46, 15, 17, 18, 37, 39, 5052]
Ca2+ ATPase [10, 15, 39]
Carbonic anhydrase [11, 39]
Paracellular transport Apical tight junctions [56]

Proton secretion for solubilization of the eggshell mineral calcite Villus cavity cells Carbonic anhydrase [16, 28, 39, 52, 53, 55, 68]
Vacuolar H+-ATPase [21]

Bicarbonate transport for acid-base homeostasis in the embryo Villus cavity cells
(i) bicarbonate reabsorption from the eggshell to the embryo AE1 anion exchanger [30]
(ii) HCO3 influx from the eggshell into the VC cells Membrane-associated carbonic anhydrase [27, 54]