Calcium reabsorption from the eggshell |
Capillary covering cells: pinocytosis model |
|
[6, 12, 13, 15, 19, 35–38, 40, 56] |
|
Tight adhesion of cell membranes to shell membrane, apical vesiscles, and endocytotic-like pits |
[4, 6, 15, 17, 31, 35, 36, 48, 56] |
|
Ca2+-binding protein |
[4–6, 15, 17, 18, 37, 39, 50–52] |
|
Ca2+ ATPase |
[10, 15, 39] |
|
Carbonic anhydrase |
[11, 39] |
Paracellular transport |
Apical tight junctions |
[56] |
|
Proton secretion for solubilization of the eggshell mineral calcite |
Villus cavity cells |
Carbonic anhydrase |
[16, 28, 39, 52, 53, 55, 68] |
Vacuolar H+-ATPase |
[21] |
|
Bicarbonate transport for acid-base homeostasis in the embryo |
Villus cavity cells |
|
|
(i) bicarbonate reabsorption from the eggshell to the embryo |
AE1 anion exchanger |
[30] |
(ii) HCO3− influx from the eggshell into the VC cells |
Membrane-associated carbonic anhydrase |
[27, 54] |