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. Author manuscript; available in PMC: 2010 Mar 22.
Published in final edited form as: Open Neurosci J. 2009 Dec 25;3:128–133. doi: 10.2174/1874082000903020128

Figure 1.

Figure 1

A schematic diagram illustrating potential functions of microtubules in dendritic spines. In addition to the proposed MT regulation of actin cytoskeleton through p140Cap and Src kinases on cortactin, MTs may also be involved in delivering membraneous organelles (e.g. mitiochondria and receptor-containing vesicles), as well as ribosome/RNA complexes, to the dendritic spine. It is likely that MTs and the actin cytoskeleton cooperate in the delivery of these cargos into spines and in the regulation of spine structure and function.