Skip to main content
. Author manuscript; available in PMC: 2011 Mar 19.
Published in final edited form as: Circ Res. 2010 Mar 19;106(5):818–832. doi: 10.1161/CIRCRESAHA.109.209197

Figure 3. Epicardial-Myocardial Signaling Pathways in Coronary Vascular Development.

Figure 3

Shown above is a schematic of the cross talk between the epicardium (blue) and myocardium (red) during the early stages of coronary development. An FGF-Shh-VEGF/Ang2 dependent pathway is important for the generation of coronary endothelial progenitors (right), while β-catenin, PDGF, TGFβ, and Thymosin β4 are important for the development of coronary vascular smooth muscle (left).