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. Author manuscript; available in PMC: 2010 Mar 22.
Published in final edited form as: J Immunol. 2006 Mar 1;176(5):2915–2923. doi: 10.4049/jimmunol.176.5.2915

FIGURE 4.

FIGURE 4

Expression of GPI-anchored CD59 on targets enhanced cytotoxicity mediated by freshly isolated human primary NK cells. A, PBMC were depleted of CD3 and proportions of NK cells (CD3−/CD56+) and CD59high populations quantified by flow cytometry. B, Following overnight activation in the presence of IFN-α, 4-h 51Cr release cytotoxicity assay was conducted against preloaded U937 cell lines at the indicated E:T ratios. Measurements are the mean of triplicate determinations. Error bars represent SE of the mean from nine independent experiments with samples from four healthy volunteers. **, p < 0.01.