A PileUp analysis was performed using the GCG SeqWeb software of the sequenced CB2 transcripts with the GenBank CB2 mRNA clones and gene sequence to determine the location of the 5′ RACE TSS (+1). Once identified, the gene region spanning approximately −40bp to +40bp of the TSSs was analyzed for core promoter elements, which is blown-up here in order to view the sequences. A. The putative core promoter of the mCB2 exon 2 transcript. B. The hCNR2 gene putative core promoter. INR, Initiator (consensus sequence YYANWYY). DPE, Downstream promoter element (consensus sequence RGWCGTG) BREd, TFIIB recognition element downstream the TATA-box (consensus sequence RTDKKKK).