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. 1997 Dec 9;94(25):14054–14059. doi: 10.1073/pnas.94.25.14054

Figure 2.

Figure 2

Competition binding profiles of IGF-I, IGF-II, and insulin against labeled [125I]IGF-I (A) and [125I]IGF-II (B) in adult rat hippocampal formation. The observed profiles clearly demonstrate [125I]IGF-I and [125I]IGF-II recognized the respective receptors at higher affinity than the related peptides. Unlabeled insulin did not compete for [125I]IGF-II binding. Each point represents the measurement of the mean ± SEM of data obtained from three to four determinations.