Fig. 5.
Cellular localization of MAG in mature oligodendrocytes at 6 day in vitro. (A–C) MAG-positive cells did not co-express A2B5 (open arrow). Co-localization of MAG was found in mature oligodendrocytes that expressed O4 (D–F, solid arrow) or MBP (G–I, solid arrow). In these cells, MAG-IR was distributed either in the cytoplasm, along the processes, or forming puncta (E, F, solid arrowhead) on the surface of membrane structures (D, F, open arrowhead). (J–L) MAG-IR (open arrow) was not found in GFAP-positive astrocytes (open arrowhead). Scale Bar: 50 µm.