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. Author manuscript; available in PMC: 2010 Mar 22.
Published in final edited form as: Cell. 2000 Oct 27;103(3):481–490. doi: 10.1016/s0092-8674(00)00139-2

Figure 1. MMP-2 and MMP-9 Are Activated during Epithelial Carcinogenesis in HPV16 Transgenic Mice.

Figure 1

Gelatin-substrate zymography of skin biopsies from ear skin of negative litter mates (norm) and K14-HPV16 transgenic mice with hyperplastic (hyp), dysplastic (dys) and Grade II SCCs. Arrows indicate location of enzymatic activity corresponding to pro- and active forms of MMP-9 and MMP-2. Molecular weight markers (kDa) are shown at left.