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Cell death (A) and total activated caspase level (B) in HAECs transfected with nonspecific or HO-2 siRNA exposed to 21% or 1% oxygen for 48 h. Cell death (C) and total activated caspase level (D) in HAECs transfected with nonspecific or HO-2 siRNA exposed to 21% or 1% oxygen for 16 h and treated with TNF-α or H2O2. Bars represent means ± S.E. (n = 5 independent experiments); *, p < 0.05 for differences from nonspecific siRNA controls.
