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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Nat Neurosci. 2009 Dec 20;13(2):205–212. doi: 10.1038/nn.2464

Table 1.

Properties of phasic and tonic GABAergic currents recorded from different cell types in wildtype and Gabrd−/− mice

Genotype Cell type n IPSC frequency (Hz) IPSC amplitude (pA) THIP-induced Itonic (pA)
WT Pyramidal 8 18.8 ± 3.3 34.8 ± 2.9 19.8 ± 3.7
Perisomatic-targeting interneuron 3 32.5 ± 6.5 40.2 ± 7.6 13.9 ± 6.2
Dendritic-targeting interneuron 4 12.9 ± 8.6 31.2 ± 3.4 23.0 ± 9.4
Non-pyramidal projection neuron 2 14.3 ± 2.4 53.4 ± 4.7 27.4 ± 15.1
δ KO Pyramidal 5 17.2 ± 1.8 42.7 ± 2.6 25.8 ± 5.9
Perisomatic-targeting interneuron 3 18.2 ± 3.8 40.5 ± 3.6 8.3 ± 2.4
Dendritic-targeting interneuron 4 10.0 ± 1.7 37.1 ± 3.7 12.7 ± 4.5
Non-pyramidal projection neuron 3 8.6 ± 0.5 38.4 ± 6.7 2.8 ± 5.7