Table 1.

Clinical Characteristics of Patients at Baseline, and at the Time of Protocol Biopsy, According to Histological Categories

	Normal n = 16	SCR n = 6	SCR+IF/TA n = 9	P
Donor age, years	41 ± 15	43 ± 23	47 ± 19	ns
Recipient age, years	51 ± 15	50 ± 04	45 ± 15	ns
Donor sex, male/female	8/8	4/2	2/7	ns
Recipient sex, male/female	10/6	5/1	7/2	ns
Number of transplant, 1st, 2 days	12/4	5/1	9/0	ns
PRA >20%	4 (25%)	1 (17%)	2 (22%)	ns
HLA mismatches	2.69 ± 1.25	2.50 ± 1.04	3.11 ± 1.45	ns
CIT, hours	21 ± 4	22 ± 3	23 ± 6	ns
ATN, no/yes	14/2	6/0	8/1	ns
Acute rejection, no/yes	14/2	4/2	4/5	0.07
At protocol biopsy
Time after transplantation, days	189 ± 106	138 ± 39	242 ± 140	ns
Serum Creatinine level, μmol/L	129 ± 28	141 ± 41	184 ± 49*	0.006
Creatinine clearance, ml/min	58 ± 11	55 ± 13	50 ± 20	ns
Proteinuria, g/day	0.22 ± 0.10	0.18 ± 0.06	0.50 ± 0.29*†	0.001

PRA indicates panel reactive antibodies; HLA, human leukocyte antigen; CIT, cold ischemia time; ATN, acute tubular necrosis. 

^*P ≤ 0.005 vs Normal (Bonferroni test); 

^†P = 0.006 vs SCR (Bonferroni test).