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. 2010 Apr;176(4):1767–1778. doi: 10.2353/ajpath.2010.090345

Figure 6.

Figure 6

Dextran-retaining cells are confined to the proximal tubules and do not express α-SMA in C57BL/6 mice. A: Proximal tubules identified by their binding with LTA (green) are labeled with a Texas-red conjugated small molecular weight dextran (red) in mice with sham-operation or UUO for 3 to 14 days. B: 89% to 98% of the proximal tubular cells retain dextran in the control and UUO groups. No statistically significant difference in dextran-retaining cells is detected between the control and UUO groups. Values represent mean ± SE. n = 3 to 5. C: Dextran-retaining cells (red) are confined inside the tubular basement membrane stained with entactin (green, top panel) and do not express myofibroblast marker a-SMA (green, bottom panel) in control and 3 to 14 days after UUO. Nuclei are counterstained with DAPI (blue). Scale bar = 20 μm.