Table 2. Comparison of RNA signal intensities.
| Gene | Two-color FISH: FSHD cell line versus control cell line (median of ratios, FSHD/normal; P-values by Wilcoxon test) | Three-color FISH: mean of ratios of affected allele versus normal allele (95% CI of median) |
|---|---|---|
| SORBS2 | 0.986 (P=0.47) | — |
| CYP4V2 | 0.504 (P=0.11) | — |
| HELT | 0.952 (P=0.82) | — |
| TLR3 | 0.924 (P=0.95) | — |
| PDLIM3 | 0.326 (P=0.0000098) | 1.035 (0.92–1.26) |
| SLC25A4 | 1.106 (P=0.39) | 1.096 (0.94–1.19) |
| FAT1 | 1.026 (P=0.96) | 0.982 (0.78–1.27) |
| LRP2BP | 0.834 (P=0.38) | 0.902 (0.66–1.23) |
| FRG1 | 0.688 (P=0.52) | 0.918 (0.72–1.33) |
| IRF2 | 0.917 (P=0.26) | 0.945 (0.76–1.14) |
| SNRPN | 9.35 (P=9.8e−26) | — |