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. Author manuscript; available in PMC: 2010 Mar 22.
Published in final edited form as: Pigment Cell Melanoma Res. 2009 Jun 5;22(4):420–434. doi: 10.1111/j.1755-148X.2009.00588.x

Figure 2.

Figure 2

Melanosomes persist into the stratum corneum in organotypic keratinocytes co-cultured with type V melanocytes: human second-passage keratinocytes from type II subjects were co-cultured at an air-medium interface with either type II or type V human melanocytes. (A, B) Electron microscopy demonstrates persistence of larger numbers of melanin particles (arrows) into the stratum corneum in cultures with type V, then with type II melanocytes (Bar = 1 μm). (C, D) Co-cultures with type V melanocytes demonstrate more melanin particles (arrows) in the stratum corneum, Fontana–Masson stain (Bars = 20 μm). (Modified from Gunathilake et al., 2009).