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. Author manuscript; available in PMC: 2010 Mar 22.
Published in final edited form as: Toxicol Pathol. 2009;37(7):969–982. doi: 10.1177/0192623309350475

Figure 6.

Figure 6

Renal immunofluorescence staining for PCNA. Pictures correspond to representative staining of kidney sections, a consistent increase in the number of PCNA positive cells was observed in the glomeruli of animals receiving AST. PCNA staining was unaffected by the estradiol status of the animal and was further increased by MPA treatment. Spironolactone and drospirenone treatment lowered the PCNA staining in AST rats. Abbreviations: ovx (ovarectomy); AST (aldosterone-salt treatment); DRO (drospirenone); MPA (medroxyprogesterone acetate); E2 (17β-estradiol); SPIRO (spironolactone).