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. 2010 Mar 23;4(3):e649. doi: 10.1371/journal.pntd.0000649

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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A total of 1,077 individuals from an endemic are of visceral leishmaniasis were tested for anti-SGS and for the combined recombinant proteins (rLJM17 + rLJM11). A, anti-SGS titers (OD). The antibodies concentrations of the positive samples were gouped into quartiles (Q). B and C, the overall performance of the serology using the recombinant proteins predicting anti-SGS positivity was estimated, and also the sensitivity of the assay according to the quartiles in positive samples. TP, true positive; FP, false positive; TN, true negative; FN, false negative; PPV, positive predictive value; NPV, negative predictive value; CI, confidence interval.