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. 2010 Feb 24;10:63. doi: 10.1186/1471-2407-10-63

Table 3.

Clinic and pathologic findings in 130 patients with CM, according to CAF-1/p60 expression in radial and vertical growth phase.

CLINICO-PATHOLOGIC FEATURES CAF-1/P60 radial growth phase CAF-1/P60 vertical growth phase
+ % ++ % +++ % PVALUE° + % ++ % +++ % PVALUE°

AGE

≤30 13 9 69,2% 4 30,8% 0 0 NS 3 23,0% 6 46,2% 4 30,8% NS

>30 117 82 70,0% 35 30% 0 0 NS 44 37,6% 40 34,2% 33 28,2% NS


STAGING

IA 25 22 88,0% 3 12,0% 0 0 <0,001 19 76,0% 3 12,0% 3 12,0% <0,001

IB 45 42 93,3% 3 6,7% 0 0 <0,001 19 42,2% 24 53,3% 2 4,5% <0,001

IIA 28 20 71,4% 8 28,6% 0 0 <0,001 9 32,1% 12 42,8% 7 25,1% <0,001

IIB 16 3 18,7% 13 81,3% 0 0 <0,001 0 0 3 18,7% 13 81,3% <0,001

IIC 4 3 75,0% 1 25,0% 0 0 <0,001 0 0 1 25,0% 3 75,0% <0,001

IIIA 4 1 25,0% 3 75,0% 0 0 <0,001 0 0 1 25,0% 3 75,0% <0,001

IIIB 7 0 0 7 100% 0 0 <0,001 0 0 0 0 7 100% <0,001

IV 1 0 0 1 100% 0 0 <0,001 0 0 0 0 1 100% <0,001


BRESLOW

<1 mm 28 25 89,3% 3 10,7% 0 0 <0,001 19 67,8% 6 21,4% 3 10,8% <0,001

1.01-2.00 mm 51 41 80,4% 10 19,6% 0 0 <0,001 21 41,2% 22 43,1% 8 15,7% <0,001

2.01-4.00 mm 41 21 51,2% 20 48,8% 0 0 <0,001 7 17,1% 14 34,1% 20 48,8% <0,001

>4.00 mm 10 4 40,0% 6 60,0% 0 0 <0,001 0 0 4 40,0% 6 60,0% <0,001


PROGNOSIS

NO PROGRESSION 95 91 95,8% 4 4,2% 0 0 <0,001 47 49,5% 46 48,4% 2 2,1% <0,001

S/N/M* 35 0 0 35 100% 0 0 <0,001 0 0 0 0 35 100% <0,001

*S: skin (dermal/hypodermal) metastasis; N: nodal metastasis; M: distant metastasis; °(P value were calculated by t-test or ANOVA)