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The baroreceptor reflex response in response to angiotensin II and nitroprusside. Nav2 hypomorphic mutants (Hom) show blunted responsivity (change in heart rate (ΔHR)/change in blood pressure (ΔBP)) at varying doses of (A) angiotensin II and (B) nitroprusside. Asterisks indicate statistical significance at P < 0.001 as determined by a two tailed t-test. WT, wild-type.
