Table 1. Quantification of peptide binding.
Cells | Peptide | R min, norm | K d (µM) | K d, ENF/K d, T-1249 |
Erythrocytes | T-1249 | −0.81±0.0063 | 4.16±0.13 | 8.5 |
Enfuvirtide | −0.97±0.015 | 35.4±1.33 | ||
PBMC | T-1249 | −0.77±0.014 | 7.71±0.61 | 8.1 |
Enfuvirtide | −1.0±0.071 | 62.2±10.2 |
Comparison of the values of the dissociation constant, K d and the parameter R min obtained by non-linear regression with equation (1). The values represent mean ± SEM.