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Changes in gene expression are shown as the fold-change relative to the levels on the day of challenge for (A) TNF-α and (B) TGF-β. (C) Spearman rank correlation of TGF-β at 4 weeks PC, for all animals, with plasma viral RNA AUC between 1 and 20 weeks PC. (λ) Naïve control macaques (n = 7), (○) SHIV-immunized macaques (n = 5) and (5) Depo-Provera®-treated, SHIV-immunized macaques (n = 6).
