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. Author manuscript; available in PMC: 2011 May 1.

Published in final edited form as: J Inorg Biochem. 2010 Jan 7;104(5):512–522. doi: 10.1016/j.jinorgbio.2009.12.022

a) Ribbon drawing of the human β2 Alcohol dehydrogenases ternary complex with NAD⁺ and 4-iodopyrazole. b) and c) Close up views of the two zinc-binding sites in 1HDY. NAD⁺ is shown in red. The two zinc centers bound with four cysteines are enclosed in red circles with the zinc atoms as spheres. The other two zinc centers bound with two cysteines, one histidine, and 4-iodopyrazole are enclosed in blue boxes with the zinc atoms as spheres.

a) Ribbon drawing of the human β2 Alcohol dehydrogenases ternary complex with NAD⁺ and 4-iodopyrazole. b) and c) Close up views of the two zinc-binding sites in 1HDY. NAD⁺ is shown in red. The two zinc centers bound with four cysteines are enclosed in red circles with the zinc atoms as spheres. The other two zinc centers bound with two cysteines, one histidine, and 4-iodopyrazole are enclosed in blue boxes with the zinc atoms as spheres.