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. Author manuscript; available in PMC: 2011 Feb 15.
Published in final edited form as: Neuroimage. 2009 Nov 26;49(4):3047–3056. doi: 10.1016/j.neuroimage.2009.11.043

Figure 5.

Figure 5

Spatially normalized tract profiles for fractional anisotropy (FA; top row) and mean diffusivity (MD; middle row), and magnetization transfer ratio (MTR; bottom row) of the left corticospinal tract from a man with relapsing-remitting multiple sclerosis. The man was 33 years old when first scanned, and 5 follow-up scans were obtained over a period of 3 years. The horizontal lines denote the position of an MS lesion that was acute at the time of first scanning and that caused temporary right hemiparesis. Tract profiles derived from conventional tractography are shown in the left column and from the tract-probability-map method in the right column. The horizontal axis depicts normalized position along the tract, ranging from the pons on the left to the subcortical white matter on the right. The solid black line shows the mean tract profile from healthy volunteers and the gray zone corresponds to the 95% confidence limits of the mean.