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MI-4 DAT binding affinity and dopamine uptake inhibition potency in N2A cells. MI-4 inhibition of [3H]-WIN 35,428 binding (upper panel) and inhibition of [3H]-dopamine uptake (lower panel) in N2A neuroblastoma cells stably expressing WT hDAT (n = 3 or more experiments for each assay). Results were analyzed with one-way ANOVA (P < 0.05) with a posthoc Dunnett’s multiple comparison test.
