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Overlay of minimized structures of raloxifene (green carbons) and compound 3 (gray carbons), raloxifene (green carbons) and 4-hydroxytamoxifen (gray carbons), and 4-hydroxytamoxifen (gray carbons) and compound 2 (green carbons). Note that overlay of the alternative rotomer of raloxifene with the alternative enantiomer of compound 3 produces a mirror image of that depicted here.
