Table 7.

Peroxisome proliferator-activated receptor (PPAR) pathwaysrelated genes down regulated in ER+ breast cancer cells in Response to AA

Symbol	Entrez gene name	Fold change
ADCY10	adenylate cyclase 10 (soluble)	−3.7
ASPN	asporin	−8.8
CD36	CD36 molecule (thrombospondin receptor)	−3.9
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	−9.6
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	−2.4
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	−5.9
FASN	fatty acid synthase	−2.6
GH1	growth hormone 1	−2.9
GHR	growth hormone receptor	−21.4
GNAS	GNAS complex locus	−15.1
HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	−2.4
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	−2.3
IL1R2	interleukin 1 receptor, type II	−4.1
IL6	interleukin 6 (interferon, beta 2)	−11.8
KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	−2.3
MAP2K3	mitogen-activated protein kinase kinase 3	−3.7
MAP3K7	mitogen-activated protein kinase kinase kinase 7	−2.3
MED1	mediator complex subunit 1	−2.3
NCOA3	nuclear receptor coactivator 3	−2.4
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	−3.8
PLCE1	phospholipase C, epsilon 1	−2.9
PLCL1	phospholipase C-like 1	−31.2
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	−10.5
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	−4.9
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	−3.2
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	−14.7
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	−13.5
RRAS	related RAS viral (r-ras) oncogene homolog	−2.3
SMAD4	SMAD family member 4	−3.6