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. 2010 Mar 3;65A(4):344–352. doi: 10.1093/gerona/glq018

Figure 5.

Figure 5.

Insulin receptor (IR) in Ames dwarf (df) mice after growth hormone (GH)/thyroxine (T4) treatment. (A) Hepatic IR messenger RNA (mRNA) in young-df saline, n = 12; old-df saline, n = 10; young-df GH and T4, n = 12; old-df GH and T4, n = 10; young-N, n = 13; and old-N n = 10. (B) Hepatic IR total protein in young-df saline, n = 11; old-df saline, n = 9; young-df GH and T4, n = 12; old-df GH and T4, n = 10; young-N, n = 13; and old-N, n = 10. (C) Hepatic phosphotyrosine 1158 IR in young-df saline (−), n = 5; young-df saline (+), n = 5; old-df saline (−), n = 5; old-df saline (+), n = 4; young-df GH and T4 (−), n = 6; young-df GH and T4 (+), n = 6; old-df GH and T4 (−), n = 5; old-df GH and T4 (+), n = 5; young-N (−), n = 7; young-N (+), n = 6; old-N (−), n = 5; old-N (+), n = 5, where (+) are animals stimulated with insulin and (−) saline control. Groups that do not share a superscript are significantly different (p < .05).