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. Author manuscript; available in PMC: 2010 Mar 23.
Published in final edited form as: Stat Interface. 2009 Jan 1;2(4):413–424. doi: 10.4310/sii.2009.v2.n4.a3

Figure 5.

Figure 5

Study B: 52 weeks survival without relapse for subjects in remission after 6 months of active treatment. k = 6 partitions. The top panels show profiles of the principal points estimated from Study A. Shown also are the numbers of Study B subjects that were classified to belong to each partition. The bottom panel shows the Phase 1 trajectories of symptoms decline of Study B patients who were in remission after 12 weeks of acute treatment. The large numbered circles present the estimated principal points from Study A. The middle panels show Kaplan-Meyer survival curves in 52 weeks after 12 weeks of acute treatment and p-values for Log-rank tests to compare relapse on continued drug vs. switching to placebo.