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. Author manuscript; available in PMC: 2010 Mar 23.
Published in final edited form as: Stat Interface. 2009 Jan 1;2(4):413–424. doi: 10.4310/sii.2009.v2.n4.a3

Table 2. Survival without relapse on drug and placebo for subjects in remission after (a) 12 weeks acute treatment for depression with drug; and (b) 12 weeks acute treatment plus 14 weeks of maintenance with drug, total of 6 months.

pp1 (a) 14 weeks survival after 12 weeks of acute treatment (b) 12 weeks survival after 6 months of treatment

Randomized to Drug Randomized to Placebo Log-Rank test Randomized to Drug Randomized to Placebo Log-Rank test

Total Relapse Total Relapse p Total Relapse Total Relapse p

k = 7

1 65 11 12 7 .0007 20 5 13 5 .2912
2 4 1 2 0 .6171 1 0 1 0 1
3 101 29 45 21 .0020 38 5 17 9 .0009
4 69 5 21 9 .0333 24 5 12 2 .9597
5 34 9 9 4 .1385 14 4 4 0 .3614
6 23 5 7 1 .6487 7 2 5 2 .6693
7 3 1 0 0 1 1 0 0

k = 6

1 56 10 10 4 .0325 16 3 12 5 .1108
2 109 31 44 22 .0007 41 8 18 8 .0312
3 56 12 22 8 .1510 19 3 11 2 .8149
4 64 16 15 6 .0779 25 6 10 3 .2843
5 4 1 1 0 1 1 0 1 0 1
6 10 3 4 2 .2924 3 2 0 0

k = 5

1 82 24 32 14 .0524 27 5 14 5 .1741
2 13 2 2 0 .6889 6 1 3 0 .4795
3 18 5 3 2 .0753 5 2 2 2 .3459
4 104 22 36 14 .0138 35 7 17 5 .3892
5 82 19 23 12 .0004 32 7 16 7 .0204

k = 4

1 73 18 18 8 .0286 27 7 13 5 .1514
2 8 1 2 0 .7237 4 1 1 0 .6171
3 71 14 15 8 .0032 20 6 14 5 .6212
4 147 40 61 26 .0021 54 8 24 8 .0239