TABLE 1.

Clinical and laboratory characteristics

	Lean	Obese	Type 2diabetes
n	8	8	12
Sex (male/female)	5/3	3/5	4/8
Age (years)	45 ± 3	44 ± 4	53 ± 3
BMI (kg/m2)	25.5 ± 1.0	30.5 ± 1.0*	31.5 ± 1.2*
Glucose (mmol/l)	5.3 ± 0.2	5.6 ± 0.1	7.7 ± 0.7*†
A1C (%)	5.0 ± 0.1	4.9 ± 0.2	6.3 ± 0.3*†
Insulin (pmol/l)	44 ± 3	126 ± 19*	85 ± 13*†
FFA (μmol/l)	430 ± 40	510 ± 50	700 ± 40*†
Insulin sensitivity index	6.5 ± 0.9	3.1 ± 0.5*	3.4 ± 0.8*
Adiponectin (μg/ml)	22.4 ± 3.0	15.4 ± 2.7*	14.8 ± 2.8*
Leptin (ng/ml)	8.6 ± 2.4	19.6 ± 3.0*	20.0 ± 3.2*
IL-6 (pg/ml)	1.2 ± 0.2	1.9 ± 0.5	2.4 ± 0.4*
VO2max (ml · kg−1 · min−1)	21.1 ± 2.3	20.8 ± 2.6	16.4 ± 0.4
Work
Low intensity (W)	54 ± 5	53 ± 4	46 ± 2
Moderate intensity (W)	79 ± 7	77 ± 6	67 ± 3

Data are mean ± SE.

^*P < 0.05 vs. lean;

^†P < 0.05 vs. obese.