(a) En face OCT and (b) OCM, obtained about 60 and 50 μm below the tissue surface, respectively, demonstrate thyroid follicles (F) with variable sizes and shapes consistent with multinodular colloid goiter. Increased cellularity, reduced amount of colloid, and large blood vessels (V) were observed. (c) and (d) are corresponding HE slides (4 and 20×, respectively). Scale bars, 500 μm in (a) and (c), and 100 μm in (b) and (d).