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2-dimentional simulation of thrombus formation in a low shear stress environment. Simulation shows changing structure of growing thrombus captured at early (a), intermediate (b), and late (c) phase of thrombus development. With time, there is a fibrin “cup” (green) developing on the thrombus surface separating procoagulant-activated platelets within the thrombus from zymogens and platelets (red) flowing in blood.
