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Chemotactic activity of mBD4:Ig and hBD2:Ig for freshly isolated mouse RPCs and human PBMs. The migration of freshly isolated mouse RPCs (a) and freshly isolated human PBMs in response to various concentrations of recombinant mBD4:Ig, hBD2:Ig and hIgG1 (b) was tested using a 48-well chemotaxis chamber assay as described under “Experimental Procedures.” Data are the means ± S.D. of one representative experiment of three, each done in triplicate. HPF, high power field.
