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HEK cells expressing ΔCR PrP are rapidly killed by G418 and Zeocin. Cells expressing ΔCR or WT PrP were treated with 400 μg/ml G418 or 250 μg/ml Zeocin for the indicated times, and viability was assayed by MTT reduction. Cell viability is expressed as the A570 value of treated cells as a percentage of the value for untreated cells. Data points are the mean values of duplicate wells from a single experiment and are representative of at least three similar experiments.
