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. Author manuscript; available in PMC: 2010 Mar 23.
Published in final edited form as: J Gen Virol. 2005 Nov;86(Pt 11):2999–3008. doi: 10.1099/vir.0.81126-0

Fig. 8.

Fig. 8

The effect of HCMV US2, US3, US6 and US11 on gpUL18 and HLA-I expression. HFFFs were infected with HCMV AD169, △UL18 or RV798 (△US2–US11). (a) Immunoblot using mAb M71 demonstrating that US2–US11 expression during productive HCMV infection had no apparent effect upon gpUL18 expression. (b) Cell surface staining, using mAbs W632, and (c) immunoblot assays, using mAb mAbs W632, showing US2–US11 expression during productive HCMV infection had a significant effect upon cell surface HLA-I. (d) Immunoblot, using the mAb MEM-E/02, showing HLA-E synthesis was significantly increased following infection with HCMV AD169, but not the US2–US11 mutant RV798.